(1) Francis Freeman, a mutant with a high tolerance for pain, also known as Ajax, is a Deadpool villain straight from Wade’s first ongoing run, first appearing in Deadpool #14.

(2) Angel Dust is a Morlock from the comics, first appearing in Morlocks #1. She can raise her adrenaline-levels to give herself super strength. 

(3) Since the timeline change, we have no idea where or when Deadpool is set. Since the change however, Colossus has changed nationalities to Russian, unlike the other movies. His X symbol on his uniform almost resembles the Black Widow emblem. 

(4) Negasonic Teenage Warhead mentions the school blowing up every year. Her appearance and powers in the comics were drastically altered for this movie and, shortly afterwards, the comics not only changed the character accordingly, but also moved her into Deadpool’s supporting cast. 

(5) The Sister Margaret School for Wayward Girls, a decidedly nasty place in the comics, is also refurbished to become the Hellhouse, the bar seen in this movie where the mercs all bet on the ‘dead pool’. In the comics, the Dead Pool was the part of the Weapon X Projects where they sent their failed test subjects. 

(6) Weasel is Wade’s science-nerd best friend in the comics. Most of the time. When they’re not trying to actively kill each other. He first appears in Cable #3.

(7) The mutant Marrow makes a cameo in the mutant lab. The organisation is unnamed, but considering it’s implied to be Logan’s healing that give Wade his ‘cure’, we can assume its the Essex Corp or Weapon X Project. They also use the inhibitor collars seen in other movies.

(8) Vanessa Carlysle in the comics is the mutant Copycat, a shape shifter who first appeared alongside Deadpool in New Mutants #98. She was posing as Domino at the time though and her true form was not seen until over a year later in X-Force #11. In the movies, she’s apparently not a mutant – but as a shapeshifter, how do we know?

(9) Blind Al is Deadpool’s roommate, first appearing in Deadpool #1. The more accurate term would be ‘prisoner.’ While her origin is relatively unknown, we know she was a former British Service Agent who Deadpool was hired to kill. Instead, he killed everyone else and took her home with him. While argumentative, they truly are a dysfunctional family. 

(10) Deadpool’s origin has elements from the comics: the cancer, the relationship with Vanessa is all accurate from the comics, as far as we can tell. Wade has given (and been given) many different accounts of his back story and even now we’re not sure anything he says is reliable. Wade Wilson is not even his birth name.

(11) The enemy solider named Bob that Deadpool stops to chat with is based on his pal Bob, Agent of HYDRA in the comics.

(12) This being a Deadpool movie there are dozens of references to other movies, some in universe, some not, other comics, franchises and even his own creators. Just some of the best examples:

Deadpool’s Fourth-Wall Fiesta: A Meta Marvel Tale

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